Inhouse product
Typhim Vi Syringe Vaccine
Typhim Vi is an injectable vaccine used for the prevention of typhoid fever, a serious bacterial infection caused by Salmonella typhi. This vaccine is designed for use in individuals aged 2 years and older and is especially important for people traveling to regions where typhoid is common.
Pharmaceutical Properties
Each pre-filled syringe of Typhim Vi contains:
25 micrograms of purified Vi capsular polysaccharide antigen from Salmonella typhi
Preservative-free, clear solution for intramuscular injection
The vaccine is inactivated and does not contain live bacteria, making it safe and non-infectious. It comes in a single-dose syringe, ready to use for efficient administration.
Indications for Use
Typhim Vi is indicated for:
Pre-exposure protection against typhoid fever in individuals aged 2 years and older
Travelers to countries or regions with high typhoid incidence
Residents of areas with poor sanitation or limited access to clean water
Lab personnel or healthcare workers at risk of exposure
It is not used for treatment, only for prevention.
Mechanism of Action
Typhim Vi works by introducing a purified form of the Vi capsular polysaccharide, which is a key component of the Salmonella typhi bacterium’s outer coating.
When injected, this antigen stimulates the immune system to produce specific antibodies. These antibodies remain in the body and provide protection by quickly attacking the bacteria if exposure occurs, thereby preventing infection and reducing the risk of severe illness.
Clinical Protocol in Dubai
In Dubai, Typhim Vi is commonly administered as a single dose at least 2 weeks before potential exposure, especially before travel to high-risk regions. The standard clinical protocol includes:
One intramuscular dose in the deltoid muscle
Booster dose every 3 years if continued risk of exposure exists
The vaccine is often required for individuals applying for travel visas or relocating to endemic countries. It may be given alongside other travel vaccines, with proper spacing between injections.
Other Characteristics
Typhim Vi is well-tolerated. Common side effects include:
Mild soreness, redness, or swelling at the injection site
Low-grade fever or headache
General fatigue or body aches
Severe reactions are rare. The vaccine does not protect against paratyphoid fever or other foodborne illnesses, so additional hygiene precautions are still necessary when traveling.
Conclusion
Typhim Vi Syringe Vaccine is an effective and essential tool for preventing typhoid fever, especially for those traveling from Dubai to areas where the disease is endemic. Its single-dose format, long-lasting immunity, and safety profile make it a reliable choice for both personal and public health protection. Following the recommended vaccination timeline ensures that individuals are well-protected and can travel with confidence. Always consult with a healthcare provider for proper guidance before international travel.
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