M-M-R II Vaccine
M-M-R II is a live attenuated viral vaccine used to provide immunity against measles, mumps, and rubella. It is a combined vaccine that helps protect individuals—primarily children—from these three highly contagious diseases with a single injection.

Pharmaceutical Properties
Each dose of M-M-R II contains live, attenuated strains of viruses:

• Measles virus (Edmonston strain)

• Mumps virus (Jeryl Lynn strain)

• Rubella virus (Wistar RA 27/3 strain)

The vaccine is presented as a freeze-dried powder that is reconstituted with a sterile diluent before administration. Each 0.5 ml dose is given subcutaneously, typically in the outer upper arm. It contains no preservatives and is free from human or animal blood products.

Indications for Use
M-M-R II is indicated for:

• Primary immunization of children aged 12 months and older

• Catch-up vaccination for older children, adolescents, and adults without prior immunity

• Travelers to regions with outbreaks or endemic disease

• Healthcare and childcare workers who need immunity verification

• Post-exposure control in outbreak situations

It is widely used as part of national immunization schedules and for international health compliance.

Mechanism of Action
M-M-R II contains weakened (attenuated) live viruses that stimulate the immune system to develop protective antibodies.

These viruses mimic natural infection without causing disease. Once vaccinated, the immune system is “trained” to recognize and destroy these viruses quickly if they ever invade the body in the future, preventing illness and its complications.

Clinical Protocol in Dubai
In Dubai, M-M-R II is administered according to the UAE’s national vaccination guidelines:

• First dose: Given at 12 months of age

• Second dose: Administered between 4 and 6 years of age

For those who missed their childhood doses, two doses may be administered at any age, spaced at least 28 days apart.

Special vaccination protocols may apply for travelers, healthcare staff, or during outbreak response. The vaccine is documented in the child’s immunization card and national health records.

Other Characteristics
M-M-R II is generally well tolerated. Mild side effects may include:

• Pain or swelling at the injection site

• Fever

• Mild rash

• Temporary joint pain (especially in post-pubertal females)

Rarely, allergic reactions or febrile seizures may occur. The vaccine is not recommended during pregnancy, and caution is advised in immunocompromised individuals.

Conclusion
M-M-R II is a vital vaccine that ensures long-term protection against three serious viral illnesses: measles, mumps, and rubella. Its combined formula simplifies immunization and supports high vaccination coverage in Dubai. With a strong safety profile and well-established protocol, M-M-R II plays a key role in public health, school readiness, and international travel compliance. Staying up to date with MMR vaccination helps protect individuals and the wider community from outbreaks.