Engerix-B 20 (Adult)
Engerix-B 20 is a vaccine specifically formulated for the prevention of hepatitis B in individuals aged 16 years and older. Hepatitis B is a contagious liver infection caused by the hepatitis B virus (HBV), and vaccination is the most effective way to prevent it.

Pharmaceutical Properties
Each dose of Engerix-B 20 Adult contains:

• 20 micrograms of recombinant hepatitis B surface antigen (HBsAg)

• Aluminum hydroxide as an adjuvant to enhance the immune response

The vaccine is produced using recombinant DNA technology in yeast cells, ensuring it is non-infectious and free from human blood products. It is presented as a suspension for intramuscular injection, usually administered in the deltoid muscle.

Indications for Use
Engerix-B 20 is indicated for active immunization against hepatitis B in:

• Adults aged 16 years and older

• Healthcare workers and medical students

• Travelers to regions with high HBV prevalence

• Individuals with chronic illnesses (e.g., diabetes, kidney disease)

• People with high-risk lifestyles or close contact with HBV-infected persons

• Pre-exposure or post-exposure prophylaxis in certain cases

The vaccine is suitable for both routine protection and occupational or situational risk groups.

Mechanism of Action
Engerix-B 20 introduces a small, non-infectious part of the hepatitis B virus—the surface antigen—into the body. The immune system recognizes this antigen as foreign and produces specific antibodies to fight it.

This creates a memory immune response that enables the body to rapidly defend against real hepatitis B virus exposure in the future, preventing infection and related liver complications.

Clinical Protocol in Dubai
In Dubai, Engerix-B 20 is administered according to international and UAE Ministry of Health guidelines. The standard adult vaccination schedule includes:

• First dose: Day 0

• Second dose: 1 month after the first

• Third dose: 6 months after the first

For rapid protection (e.g., in travelers or emergency situations), an accelerated schedule may be used:

• Doses at 0, 7, and 21 days, followed by a booster at 12 months

All doses are given intramuscularly, and vaccination records are maintained for proof of immunization, especially for healthcare workers or those traveling abroad.

Other Characteristics
Engerix-B 20 is well-tolerated in most individuals. Common side effects include:

• Mild pain, redness, or swelling at the injection site

• Headache or fatigue

• Low-grade fever or general discomfort

Severe allergic reactions are extremely rare. The vaccine contains no live virus, no preservatives, and is safe for immunocompromised adults under medical supervision.

Conclusion
Engerix-B 20 (Adult) is a safe and effective way to protect adults from hepatitis B, a potentially serious and chronic liver disease. In Dubai, it is widely used across medical centers, hospitals, and clinics for routine adult immunization, occupational protection, and pre-travel safety. By following the recommended schedule, adults can ensure long-term immunity and peace of mind. Always consult a healthcare provider for personalized advice and timely vaccination.