Havrix 1440 is a highly effective inactivated hepatitis A virus vaccine designed to prevent hepatitis A infection. Hepatitis A is a contagious liver disease caused by the hepatitis A virus (HAV), which can lead to symptoms like fatigue, nausea, abdominal pain, and jaundice. This vaccine is recommended for long-term protection by triggering the immune system to develop antibodies against HAV.

What is Havrix 1440?

Havrix 1440 is formulated for individuals aged 12 months and older and is administered as a two-dose series to provide immunity against hepatitis A virus. The vaccine contains inactivated hepatitis A virus produced in human diploid cells, ensuring safety and effectiveness.

Pharmaceutical Properties and Storage of Havrix 1440

• Formulation: Each dose contains 1440 ELISA units of inactivated hepatitis A virus.

• Presentation: Sterile suspension for intramuscular injection.

• Storage: Keep refrigerated between 2°C to 8°C; do not freeze and protect from light.

• Stability: Maintain cold chain to ensure vaccine potency until the expiration date.

Indications for Havrix 1440 Vaccine Use

Havrix 1440 is indicated for:

• Travelers to hepatitis A endemic areas.

• Individuals with chronic liver diseases such as cirrhosis or chronic hepatitis B/C.

• People working in food preparation, healthcare, or high-risk environments.

• Men who have sex with men and persons with injection drug use behaviors.

• Close contacts of acute hepatitis A patients.

• Those exposed to contaminated water or poor sanitation conditions.

How Does Havrix 1440 Work?

The vaccine stimulates the immune system to produce protective antibodies against hepatitis A virus. Since the virus in the vaccine is inactivated, it cannot cause disease but helps the body develop a rapid immune response upon future exposure to HAV.

Havrix 1440 Clinical Protocol in Dubai

• Dosage: Two doses, 6-12 months apart.

• Administration: Intramuscular injection, usually in the deltoid muscle.

• Eligibility: Individuals aged 12 months and older at risk for hepatitis A infection.

Contraindications and Precautions

• Contraindications: Severe allergic reactions to vaccine components or hypersensitivity.

• Precautions: Delay vaccination if moderately or severely ill; consult healthcare providers if pregnant or breastfeeding.

Side Effects of Havrix 1440

Common side effects include:

• Injection site pain or redness

• Mild fever

• Fatigue and headache

Severe allergic reactions are rare but require immediate medical attention.

Post-Vaccination Monitoring

Patients should be observed for a short period post-vaccination to monitor for any immediate adverse reactions.

Why Choose Havrix 1440? Key Benefits

• Long-lasting immunity: Protection for at least 20 years.

• Safe and well-tolerated: Mild and temporary side effects.

• No live virus: Zero risk of contracting hepatitis A from the vaccine.

• Recommended by health authorities worldwide and used extensively in travel medicine and public health.

Conclusion: Havrix 1440 Vaccine for Hepatitis A Prevention

Havrix 1440 is a safe, effective, and long-lasting vaccine critical in preventing hepatitis A infection, particularly for travelers, healthcare workers, and those with liver conditions. Its inclusion in vaccination programs, including in Dubai, helps reduce the global burden of hepatitis A by providing reliable immunity against this contagious liver disease.